Analysis of Pathogenesis and Prescription Formulating Principle of Traditional Chinese Medicine Prevention and Treatment Plan for COVID-19 / 中国实验方剂学杂志

Since the outbreak of coronavirus disease 2019 (COVID-19), the health authorities in various regions have formulated a group of traditional Chinese medicine (TCM) diagnosis and treatment programs based on the consensus analysis of etiology and pathogenesis of TCM experts, and recommended the guiding prescriptions for different syndromes in three stages of prevention, treatment and recovery. In order to effectively summarize the understanding of the pathogenesis of each scheme and the rules of the formulation of various prescriptions, based on 49 TCM prevention and treatment plans issued by the health administration departments, 308 TCM prescriptions were sorted by stages (151 prescriptions in the treatment period, 118 prescriptions in the prevention period and 39 prescriptions in the recovery period). The 2019-nCoV pneumonia prescriptions was further processed by using TCM inheritance platform system. The common syndromes and the frequency of commonly used Chinese medicines were summed up. The commonly used drug pairs and combinations in different stages were extracted, and their association rules were analyzed. The rules of the Chinese herbal prescription for COVID-19 were preliminarily summarized. During the treatment period, the main syndrome types are inner blocking causing collapse, epidemic toxin in the lung, cold dampness in the lung and toxic heat in the lung, involving 187 kinds of herbs, 29 kinds of herbs with single taste frequency more than 20 times.Armeniacae Semen Amarum is the most frequently used, Gypsum Fibrosum-Armeniacae Semen Amarum is the most frequently used drug-pair, the core formula is Maxing Shigan Tang, and the main pathogenesis is cold, wet and heat. There is no unified syndrome type in the prevention period, involving 119 herbs in total. There are 13 kinds of herbs with single taste frequency more than 20 times. The most frequently used is Astragali Radix. The most frequently used medicine pair is Astragali Radix-Saposhnikoviae Radix. The core formula is Yupingfeng San, and the main pathogenesis is Qi deficiency. During the recovery period, the main syndromes are deficiency of lung and spleen Qi deficiency and Qi and Yin deficiency, involving 113 herbs, 12 kinds of herbs with single taste frequency more than 10 times, Poria with the highest frequency of use, Citri Reticulatae Pericarpium-Poria with the highest frequency of drug pairing, Erchentang and Shengmaiyin with the main pathogenesis of deficiency of spleen Qi and Yin. The purpose of this study is to provide multiple references for strengthening clinical precise treatment, improving the effect of TCM treatment and promoting the management of TCM prevention and control resources.

Progress on the research of regulation effect of fibroblasts with acupuncture-moxibustion / 中国针灸

Twenty-one Chinese literatures and 10 English literatures are included through retrieval of the full text journal database and degree paper database of CNKI and PubMed (1979-2011) in this paper. And the result indicats that regulative effect can be produced on local fascia tissue, corresponding viscera or the form, proliferation of fibroblast and extracellular matrix related factor at acupoints of healthy or pathological rat-oriented animal model through needling, electroacupuncture, moxibustion and pressure. And it has gradually developed into a new tendency of research on acupuncture-moxibustion mechanism.

Three-dimensional reconstruction of the meridians with MRI picture in the upper limb of human / 中国针灸

To explore the material basis and anatomy constitution of meridian in Chinese medicine so as to probe the essence of meridian. Based on the pictures obtained with the 3.0T MRI, the habitat of fascial connective tissue in the upper limb of human was marked and the structure was reestablished through the picture division and the three-dimensional reconstruction. This structure is similar to the meridian as recorded in the Chinese medicine in contrast to the pathway of each other. Thus, fascial connective tissue in whole body might be the anatomic basis for the meridian in Chinese medicine.